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Amphiphilic block copolymer nanoparticles are conjugated with uropathogenic  Escherichia coli  type 1 pilus adhesin FimH(A) through amidation chemistry to enable bladder epithelial cell binding and internalization of the nanoparticles in vitro.

Synthetic Polymer Nanoparticles Conjugated with FimHA from E. coli Pili to Emulate the Bacterial Mode of Epithelial Internalization

Synthetic Polymer Nanoparticles Conjugated with FimH_A from E. coli Pili to Emulate the Bacterial Mode of Epithelial Internalization