Open AccessIdentification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen
Author(s) -
Maria Kuzikov,
Elisa Costanzi,
Jeanette Reinshagen,
Francesca Esposito,
Laura Vangeel,
Markus Wolf,
Bernhard Ellinger,
Carsten Claussen,
Gerd Geißlinger,
Angela Corona,
Daniela Iaconis,
Carmine Talarico,
Candida Manelfi,
Rolando Cannalire,
Giulia Rossetti,
Jonas Goßen,
Simone Albani,
Francesco Musiani,
Katja Herzog,
Ye Yang,
Barbara Giabbai,
Nicola Demitri,
Dirk Jochmans,
Steven De Jonghe,
Jasper Rymenants,
Vincenzo Summa,
Enzo Tramontano,
Andrea R. Beccari,
Pieter Leyssen,
Paola Storici,
Johan Neyts,
Philip Gribbon,
Andrea Zaliani
Publication year - 2021
Publication title -
acs pharmacology and translational science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.271
H-Index - 10
ISSN - 2575-9108
DOI - 10.1021/acsptsci.0c00216
Subject(s) - drug repositioning , vero cell , protease , repurposing , chemistry , enzyme , viral replication , small molecule , covid-19 , drug discovery , pharmacology , in vitro , virology , biology , stereochemistry , computational biology , drug , biochemistry , virus , medicine , infectious disease (medical specialty) , disease , ecology , pathology