Open AccessAntibody Conjugation of Fluorescent Nanodiamonds for Targeted Innate Immune Cell Activation
Author(s) -
Lorena P. SuarezKelly,
Steven Sun,
Casey Ren,
Isaac V. Rampersaud,
David Albertson,
Megan Duggan,
Tiffany Noel,
Nicholas B. Courtney,
Nathaniel J Buteyn,
Charles Moritz,
Lianbo Yu,
Vedat Yıldız,
Jonathan P. Butchar,
Susheela Tridandapani,
Arfaan Rampersaud,
William E. Carson
Publication year - 2021
Publication title -
acs applied nano materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 29
ISSN - 2574-0970
DOI - 10.1021/acsanm.1c00256
Subject(s) - immune system , antibody , innate immune system , in vivo , immunology , cancer research , biology , microbiology and biotechnology
fluorescent nanodiamonds (FND) are nontoxic, infinitely photostable nanoparticles that emit near-infrared fluorescence and have a modifiable surface allowing for the generation of protein-FND conjugates. FND-mediated immune cell targeting may serve as a strategy to visualize immune cells and promote immune cell activation.