Open AccessGPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor
Author(s) -
Anna Shiriaeva,
Daejin Park,
Gyudong Kim,
Yoonji Lee,
Xiyan Hou,
Dnyandev B. Jarhad,
Gibae Kim,
Jinha Yu,
Young Eum Hyun,
Woomi Kim,
ZhanGuo Gao,
Kenneth A. Jacobson,
Gye Won Han,
Raymond C. Stevens,
Lak Shin Jeong,
Sun Choi,
Vadim Cherezov
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c00462
Subject(s) - agonist , chemistry , adenosine , adenosine receptor , antagonist , g protein coupled receptor , receptor , partial agonist , stereochemistry , pharmacology , biochemistry , medicine
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom