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Personalised treatments for depression are very much needed, because all psychological and pharmacological treatments seem to be equally effective in the aggregate even thoughwe know that treatment effectiveness varies substantially at the level of the individual patient.We are presently, unable to predict which patients will benefit from which treatments, making it necessary to use a trial and error approach to the treatment that is almost certainly implicated in the high rates of treatment dropout found among patients in treatment for depression and delays recovery for those patients who persist with treatment until a helpful modality is found for them. Personalised treatments hold out the promise of solving this problem by predicting which patients will benefit the most from which treatments. Accurate prediction of this sort would bring us a step closer to more effective treatments, which is very much needed because treatments are effective but by far not effective enough. Unfortunately, despite the attempts from several research areas, not much success has been made in the development of personalised treatment and until now very little personalised advice has been incorporated in treatment guidelines. Kessler and colleagues suggest thatwemayhave finally comea step closer todeveloping true personalised treatments that can be used in clinical practice (Kessler et al. 2016). Will we finally be able to take this important step in developing better treatment for depressive disorders? The need for personalised treatment of depression

Are personalised treatments of adult depression finally within reach?