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THE organism of pleuropneumonia of cattle was first described by Nocard & Roux in 1898. Twenty-five years later, in 1923, a second species of this group, the organism of agalactia of sheep, was discovered by Bridre & Donatien. Two additional types of this group of microbes were isolated from lungs of dogs by Shoetensack in 1934 and 1936. In 1935 and 1936 the writer described another organism, related to pleuropneumonia, and living in symbiosis with a streptobacillus in the association known as Streptobacillus moniliformis. Together with Steabben the writer reported in 1937 the occurrence of a similar organism in lung lesions of rats. Recent publications of Laidlaw & Elford (1936), Seiffert (1937 a, b), Dienes & Edsall (1937) and Gerlach (1937) have revealed the fact that a number of pleuropneumonia-like organisms, some non-pathogenic, others pathogenic, exists and can be isolated from various materials, such as soil, sewage, or lesions in animals and human beings. Further progress in our knowledge of the group must depend on the elaboration of differential methods, and the writer in the study here presented places on record the results of an investigation of this problem.

Pleuropneumonia-like organisms of diverse provenance: some results of an enquiry into methods of differentiation