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In this chapter we discuss the population and spectral synthesis of stellarpopulations. We describe the method required to achieve such synthesis anddiscuss examples where inclusion of interacting binaries are vital toreproducing the properties of observed stellar systems. These examples includethe Hertzsprung-Russell diagram, massive star number counts, core-collapsesupernovae and the ionising radiation from stellar populations that power bothnearby HII regions and the epoch of reionization. We finally offer somespeculations on the future paths of research in spectral synthesis.

Population and spectral synthesis: it doesn't work without binaries