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Objective To describe the effect of combined oral contraceptives (COC) on serum AMH level in 2 women. Methods The COC was initially stopped after over 12 years use then restarted, with the serum being analysed by 6–8 laboratories in an EQA scheme using the same assay (Beckman Coulter Gen II). Results In both women, the AMH rose significantly after cessation of the pill, and then dropped after resumption. Conclusions In summary, AMH was affected by the combined oral contraceptive pill and further studies on the effect of oral contraceptives are warranted.

asian pacific journal of reproduction

Two case studies assessing the effect of oral contraceptive pills upon serum AMH concentrations: Results from an external quality assurance (EQA) scheme