English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Objective: To evaluate the phytochemical profile and potential anti-oxidant properties of\udDacryodes edulis and Ficus exasperata.\udMethods: Six groups of Albino rats were intoxicated with tetrachloromethane (CCl4) for 2 d,\udprior to 7 d administration of 50 mg/kg, 100 mg/kg, 200 mg/kg ethanol extracts of plants and three\udcontrol remidies which is Tween 80 (placebo), CCl4 (negative control) and vitamin E (positive\udcontrol). Tissue homogenates were employed in assessing the thiobarbituric acid reactive\udsubstances expressed as malondialdehyde (MDA) levels, reduced glutathione (GSH) and catalase\ud(CAT) activities.\udResults: Phytochemical profiling of the plants showed the presence of reducing sugars,\udflavonoids, saponins and tannins, except alkaloids and terpenoids in F. exasperata and cardiac\udglycosides in D. edulis. Generally, significantly different values (P<0.05) were recorded for blood\udthan for liver homogenates. Elevated MDA levels were observed for the CCl4 treated group (negative\udcontrol). However, lower MDA levels comparable to vitamin E (positive control) were recorded for\udall D. edulis and the 200 mg/kg F. exasperata pre-treatments. CAT levels were significantly (P<0.05)\udraised in the 100 mg/kg and 200 mg/kg pretreatments for blood and the 200 mg/kg pretreatments\udfor liver, than for Vit E. CCl4 reduced GSH levels were reversed significantly (P<0.05) in blood\udby D. edulis and by the 100 mg/kg and 200 mg/kg F. exasperata pretreatments in blood and liver\udtissues. The mean dose-dependent analysis shows increasing fall in MDA levels with dosage.\udConclusions: The plant extracts exhibited dose-dependent oxidative stress suppressive action.\udThis may justify their use for the traditional preparation of anti-malarial remedies

Assessment of In vivo antioxidant properties of Dacryodes edulis and Ficus exasperata as anti-malaria plants