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Objective: To evaluate the diagnostic efficacy of ischemia modified albumin (IMA) and its\udcorrelation with lipid profile, oxidative stress in acute myocardial infarct (AMI) patients\udattending Cardiology Emergency Department (ED). Methods: At presentation serum IMA in\udconjunction with electrocardiogram (ECG) and cardiac troponin T (CTnT) was evaluated in 35\udAMI patients attending the ED within 6 hours of chest pain. These patients were subjected to\udstandardized diagnostic procedures and treatment. Thirty five healthy volunteers were enrolled\udas control. Results: IMA showed a higher level in ischemic patients than in control with the\udhighest sensitivity (77%) in comparison to CTnT and ECG. With CTnT or ECG, IMA documented a\udsensitivity of 83% and 88%, respectively. Whereas with both CTnT and ECG, IMA identified 94% of\udAMI patients with the highest negative predictive value (90%). Conclusions: IMA has evolved as\uda cost effective, highly sensitive, early diagnostic marker of cardiac ischemia and an earlier rule\udout test in AMI patients

asian pacific journal of tropical disease

Diagnostic efficacy of ischemia modified albumin and its correlation with lipid profile, oxidative stress in acute myocardial infarct patients on admission