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The Human Genome Project (HGP) was predicted to catapult medical research into the new millennium1. The human genome is a sequence of bases encoding every gene in the body. The initial rewards have arisen from analysis of this data to determine the function of these genes2, as well as deciphering genes arising from what was once thought of as ‘junk’ DNA.3 This has helped to establish the genetic basis of disease and then to inform novel approaches to drug design and treatment. This has yielded the concepts of genetic testing, gene therapy and pharmacogenomics – all have held much promise but have we begun to see actual clinical benefit?

Has the Human Genome Project Delivered for Healthcare?