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RATIONAL AND PURPOSE: Hemophagocytic syndrome (HLH), a rare disease characterized by inappropriate activation of macrophages resulting in phagocytosis of all bone marrow derived cells, mainly occurs in immunocompromised hosts. IBD patients treated with immunosuppressive drugs have an increased risk to develop HLH. The aim of our study was to describe the characteristics of patients with IBD associated with HLH and determine the prognosis.

P496 Hemophagocytic syndrome during inflammatory bowel disease (IBD): a serious and unfamiliar complication of immunosuppressive therapy