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Aim: This study, part of the COSCOL study, aimed to establish the types of colectomies and the number of stages for ulcerative colitis (UC) performed in this population with a high previous use of immunomodulators. Design and Methods: A retrospective audit was undertaken at 35 Spanish centres which reviewed the medical records of UC patients who had undergone total colectomy between 2000 and 2005. Patients were followed up for a period of at least 24 months after the initial colectomy and data were recorded for all surgeries needed to complete the staged procedure. Results: 209 patients with total colectomy due to UC were included (44.5% women, mean age 41.6 ± 13.2 years at initial colectomy). Mean duration of the disease was 5.0 ± 6.3 years. UC was left-sided in 19.6% and extensive in 80.4%. Early surgery, defined as colectomy performed within the first two years of disease, was recorded in 77 patients (36.8%). 143 patients (68.4%) received immunomodulators (30.8% azathioprine and/or mercaptopurine and/or methotrexate only, 28% cyclosporine only, and 41,2% were receiving both). In 46.9% of patients the initial colectomy was performed as an emergency surgery. Table I shows the types of colectomy performed and the number of stages needed to complete the procedure. Conclusions: Although restorative proctocolectomy with IPAA has become the gold standard surgery for UC, it was only performed in 54% patients. Colectomy due to UC places a high burden on the patient: in 75% of patients at least two operations are required to complete it, and in 25% at least three. As many as 41% of patients carry a permanent ileostomy. Table I: Type of colectomy and number of stages performed

P099 - Postcolectomy burden in ulcerative colitis patients undergoing colectomy