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Thromboembolic disease is a major cause of morbidity and mortality in many countries. Our previous study found that Chinese subjects carried the same polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene as described in Western studies. The aim of the present study was to determine the influence of MTHFR polymorphism, B vitamins and other factors on plasma homocysteine (Hcy) levels and risk of thromboembolic disease in Chinese.

journal of the chinese medical association

Influence of Methylenetetrahydrofolate Reductase ( MTHFR ) C677T Polymorphism, B Vitamins and Other Factors on Plasma Homocysteine and Risk of Thromboembolic Disease in Chinese