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There are a number of cases in high throughput screening systems where a controlled environment is desired. These include incubation periods for cell-based assays, incubation for protein detection assays such as ELISA or fluorescence assays, and branching assays for mRNA detection. In addition, as the density of wells in microplates increases and well volumes become smaller, evaporation becomes a concern in all assays.    The cytomat® 6000 is a robot accessible, automated CO 2  incubator used for cell-based High Throughput Screening systems. The incubator provides superior environmental conditions, due to the unique access door at the back of the instrument, the PlateShuttle (see Figure 3 ). This small access opening insures that the environment inside the system (temperature, humidity and CO 2 ) is undisturbed as microplates are accessed ( Figure 2 ).    The system provides high speed, random (bar-coded) access to all microplate formats for 24, 96, 384 and 1536 well microplates (up to 261-microplate capacity). Other cytomat configurations offer refrigerated and low humidity environments.

Heraeus cytomat® 6000 Series Incubators and Storage Systems from Kendro Laboratory Products