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Glycolysis-from-glycose may be more beneficial than glycogenolysis in protecting hearts against ischemia. We tested the hypothesis that ischemic preconditioning is mediated by increased exogenous glucose use during low-flow ischemia, an effect triggered by adenosine A1 receptor activation.

Ischemic preconditioning and glucose metabolism during low-flow ischemia: Role of the adenosine A1 receptor