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Arterial remodeling has been suggested as the predominant factor in restenosis. However, the time course and morphometric factors that determine whether remodeling occurs remain unclear. We hypothesized that arterial remodeling does not occur in all arteries following balloon injury and is dependent on neoadventitial formation.

Time course and importance of neoadventitial formation in arterial remodeling following balloon angioplasty of porcine coronary arteries