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Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia-reperfusion situation. The present study was designed to investigate, separately, the consequences of platelet adhesion and degranulation during myocardial reperfusion.

Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts