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To test the hypothesis that mild hypothermia potentiates the cardioprotection afforded by ischaemic preconditioning so that infarct size limitation can be obtained after coronary artery occlusion (CAO) durations which exceed the cardioprotective range (&gt; 90 min) of either hypothermia or ischaemic preconditioning alone.

Hypothermia extends the cardioprotection by ischaemic preconditioning to coronary artery occlusions of longer duration