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Kv4.2 subunits are major components of transient outward K(+) channels in cardiac myocytes and somatodendritic A-type channels in neurons. To identify molecular mechanisms underlying transcriptional regulation of Kv4.2 gene, we have isolated and characterized the promoter for the rat Kv4.2 gene.

GATA and FOG2 transcription factors differentially regulate the promoter for Kv4.2 K+ channel gene in cardiac myocytes and PC12 cells