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Inhibition of Na(+)-H(+) exchange (NHE) delays the onset of myocardial rigor contracture during ischemia. The aim of this study was to analyse the effects of NHE inhibition on cell-to-cell electrical uncoupling during myocardial ischemia/reperfusion.

Pre-treatment with the Na/H exchange inhibitor cariporide delays cell-to-cell electrical uncoupling during myocardial ischemia