English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

ObjectiveTo analyze the impact of I/D polymorphism of the angiotensin-converting enzyme gene on the responses of 24 h blood pressure, heart rate variability and nitric oxide after moderate aerobic exercise session.MethodTwenty seven hypertensive elderly were genotyped for the I/D polymorphism of the angiotensin-converting enzyme gene (D/D: n=9; I/D: n=9; I/I: n=9) and performed a bout of aerobic exercise at 90% of anaerobic threshold. Measurements of mean blood pressure, heart rate variability and nitric oxide were performed before and during 24h post-aerobic exercise session.ResultsThe D/D genotype showed impaired mean arterial pressure responses (elevation) in the nocturnal sleep (10:30pm to 06:30am) post-aerobic exercise when compared to rest (D/D= −4.2±8.1mmHg; p>0.05, I/D=−9.2±9.1mmHg; p<0.05 and I/I=−7.0±6.9mmHg; p<0.05). Besides, in day time of 06:30am to 10:30am (next day) higher values of mean arterial pressure responses occur between D/D=4.7±4.6mmHg vs. I/D=−2.0±13.0mmHg; p<0.05. The carriers of the D allele, in addition to not release nitric oxide significantly post-aerobic exercise session (p>0.05), showed reduced elevation of nitric oxide between genotypes immediately after aerobic exercise (D/D=12.8±135.3μM and I/D=−8.7±69.0μM vs. I/I=132.9±188.7μM; p<0.05). Reduced elevation of heart rate variability post-aerobic exercise session occurred when compared to rest (D/D=1h: −0.08±0.09s; p<0.05 and 24h: −0.08±0.11s; p<0.05).ConclusionElderly hypertensive individuals carrying the D/D genotype of the angiotensin converting enzyme gene showed impaired responses of blood pressure post-aerobic exercise, especially during sleep, and reduced heart rate variability during the 24h post-aerobic exercise. Besides, to angiotensin converting enzyme genotypes with the presence of D allele (D/D and I/D) was impaired release of nitric oxide post-aerobic exercise session

revista andaluza de medicina del deporte

Impact of ACE I/D gene polymorphism on blood pressure, heart rate variability and nitric oxide responses to the aerobic exercise in hypertensive elderly