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We study the $B_c^+$ production in Pb-Pb collisions at $\sqrt{s_{NN}}=5.02$TeV. In the quark-gluon plasma (QGP) produced in heavy-ion collisions, heavyquarks make random motions with the energy loss. We employ the Langevinequations to study the non-equilibrium distributions of heavy quarks and theInstantaneous Coalescence Model (ICM) to study the hadronization process. Dueto abundant charm and bottom quarks in the QGP, their coalescence probabilityis significantly enhanced compared with the situations in proton-protoncollisions. We find that the final production of $B_c^+$ is increased by thecoalescence process, which makes the nuclear modification factor ($R_{AA}$) of$B_c^+$ larger than the unit. Our model explains the experimental data well atsemi-central and central collisions. The observation of $R_{AA}(B_c^+)>1$ isregarded as an evident and strong signal of the existence of the deconfinedmedium generated in heavy-ion collisions.

$B_c^+$ Formation from Random Charm and Anti-bottom Quarks in the Quark-Gluon Plasma