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We consider large classes of chiral extensions of the Standard Model,including new quark generations that do not involve additional neutrinos aswell as lepton generations without quarks. An analysis of renormalization flowsof Yukawa and quartic scalar couplings reveals that additional quarks are notcompatible with a scenario of grand unification without violating the strongbounds from direct and Higgs searches at colliders. Constraints from directsearches, electroweak precision observables, and Higgs physics, together withthe assumption that additional new physics beyond the extended chiral fieldcontent should enter significantly above the TeV scale, allows us to makepredictions for searches at the LHC.

Theoretical constraints on new generations with and without Quarks or Neutrinos