Testing preexisting antibodies prior to AAV gene transfer therapy: rationale, lessons and future considerations
Author(s) -
Jerry R. Mendell,
Anne M. Connolly,
Kelly J. Lehman,
Danielle A. Griffin,
Sohrab Khan,
Sachi D. Dharia,
Lucía QuintanaGallardo,
Louise R. RodinoKlapac
Publication year - 2022
Publication title -
molecular therapy — methods and clinical development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.285
H-Index - 32
ISSN - 2329-0501
DOI - 10.1016/j.omtm.2022.02.011
Subject(s) - genetic enhancement , antibody , transduction (biophysics) , transgene , immunology , neutralizing antibody , virology , immune system , adeno associated virus , virus , immunity , gene delivery , biology , vectors in gene therapy , viral vector , medicine , vector (molecular biology) , gene , recombinant dna , genetics , biochemistry
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