Espinogénesis en motoneuronas de la médula espinal tras la lesión farmacológica de la corteza motora de ratas
Author(s) -
Néstor I. Martínez-Torres,
David González-Tapia,
Mario Eduardo Flores-Soto,
Nallely Vázquez-Hernández,
Hermelinda SalgadoCeballos,
Ignacio GonzálezBurgos
Publication year - 2018
Publication title -
neurología
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 36
eISSN - 1578-1968
pISSN - 0213-4853
DOI - 10.1016/j.nrl.2017.12.003
Subject(s) - corticospinal tract , synaptophysin , motor cortex , dendritic spine , medicine , neuroscience , spinal cord , neuroplasticity , pyramidal tracts , amyotrophic lateral sclerosis , postsynaptic potential , anatomy , biology , pathology , stimulation , magnetic resonance imaging , immunohistochemistry , disease , diffusion mri , hippocampal formation , radiology , receptor
Motor function is impaired in multiple neurological diseases associated with corticospinal tract degeneration. Motor impairment has been linked to plastic changes at both the presynaptic and postsynaptic levels. However, there is no evidence of changes in information transmission from the cortex to spinal motor neurons.
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