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The G84E variant of HOXB13 was recently found to be associated with a significantly increased risk of prostate cancer in a case control study. We estimated the prevalence of this mutation in a clinical population of men at risk for prostate cancer who were scheduled to undergo prostate biopsy.

Testing for the Recurrent HOXB13 G84E Germline Mutation in Men with Clinical Indications for Prostate Biopsy