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Previous research suggests that a failure of opioid inhibition may contribute to chronic bladder pain. We determined how acute adult and/or prior early in life exposure to bladder inflammation alters the adult content of endogenous opioid peptides in the bladder, spinal cord and blood.

Early in Life Bladder Inflammation Alters Opioid Peptide Content in the Spinal Cord and Bladder of Adult Female Rats