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Antimuscarinic drugs increase bladder capacity without prominent side effects such as urinary retention even when administered to patients with mild to moderate bladder outlet obstruction. Some mechanisms might exist in the urethra to compensate for the emptying function of the detrusor after the administration of antimuscarinic drugs. We investigated the influence of the antimuscarinic drug propiverine (Taiho Pharmaceutical, Tokyo, Japan) on urethral function.

the journal of urology

Antimuscarinic Drug Inhibits Detrusor Overactivity Induced by Topical Application of Prostaglandin E <sub>2</sub> to the Urethra With a Decrease in Urethral Pressure

Antimuscarinic Drug Inhibits Detrusor Overactivity Induced by Topical Application of Prostaglandin E 2 to the Urethra With a Decrease in Urethral Pressure

Antimuscarinic Drug Inhibits Detrusor Overactivity Induced by Topical Application of Prostaglandin E ₂ to the Urethra With a Decrease in Urethral Pressure