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Type 1 neurofibromatosis (NF1), previously known as von Recklinghausen disease, is a single genetic disorder characterized by neurofibromas and hyperpigmented skin lesions. The clinical manifestations of NF1 are extremely variable. Vascular involvement, although rarely encountered, can cause fatal spontaneous hemorrhage. The following describes a rare case of giant NF1 in the soft tissue of the chest wall presenting with massive spontaneous hemorrhage.

Massive spontaneous hemorrhage in giant type 1 neurofibromatosis in soft tissue of chest wall