English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Open

Presents the pdf analysis as premium feature

PDF Analysis

Insights

Presents the summarisation as premium feature

Summarisation

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

ith the rapid growth in the elderly segment of the population, an increasing number of older patients will have end-stage heart failure and require car- dia csurgery. 1Th edemographi co fpatient sunder- going left ventricular assist device (LVAD) implantation is ex- pected to shift toward older and sicker patients in parallel. This study was designed to determine the effect of advanced age on postimplantation complications, bridge-to-transplantation rates, and posttransplantation survival in LVAD recipients. Patients and Methods Two hundred one patients undergoing LVAD implantation at a single center from July 1996 through April 2004 were retrospec- tively reviewed. Patients were categorized according to 3 age cohorts: group 1, less than 40 years; group 2, 40 to 59 years; and group 3, 60 years or older. These groups were then compared with regar dt obaselin echaracteristics ,LVA Dscores, 2postoperative complications, bridge-to-transplantation rates, and posttransplan- tation survival. Data were represented as frequency distributions and percent- ages. Values of continuous variables were expressed as means SD. Continuous variables were compared by the analysis of vari- ance test, whereas nominal variables were compared using 2 tests. Kaplan-Meier analysis was used to calculate long-term survival alon gwit hlog-rank P value swhe ncomparin ggroups. 3Significant predictors of bridge to transplantation were identified by logistic regression models. All data were analyzed with SPSS 11.5 soft- ware (SPSS, Inc, Chicago, Ill). Results Demographics. Clinical characteristics of patients are shown i nTabl e1 .Th enumbe ro fpatient si ngroup s1 ,2 ,an d3 wa s41 (20.4%), 104 (51.7%), and 56 (27.9%), respectively. There were no significant differences in sex, mean body mass index, and mean LVAD score among the 3 groups. Coronary artery disease as the cause of heart failure was significantly more common in older patients, whereas idiopathic cardiomyopathy and other causes were significantly more common in younger cohorts. There was a greater incidence of hypertension in older patients undergoing LVAD implantation. Postoperative complications and bridge-to-transplanta-

Bridging to transplantation with left ventricular assist devices: Outcomes in patients aged 60 years and older