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Atrial fibrillation occurs in 20% to 40% of patients after cardiac surgery, but its pathophysiology remains unclear. Recent studies demonstrated preexisting histologic markers that portend the development of postoperative atrial fibrillation. In this prospective study, we focused on mitochondrial dysfunction in response to ischemic stress as a potential predictor for postoperative atrial fibrillation.

journal of thoracic and cardiovascular surgery

Impaired mitochondrial response to simulated ischemic injury as a predictor of the development of atrial fibrillation after cardiac surgery: In vitro study in human myocardium