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Standardization of exercise intensity and consideration of a dose response is essential. Commentary on “Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models”, by Lourenco et al., published 2019 in Nature Medicine Thomas Gronwald *, Ana Cristina de Bem Alves , Eric Murillo-Rodr ıguez , Alexandra Latini , Juliane Schuette , Henning Budde d a Faculty of Health Sciences, Department of Performance, Neuroscience, Therapy and Health, Medical School Hamburg, University of Applied Science and Medical University, Hamburg 20457, Germany b LABOX, Department of Biochemistry, Center for Biological Sciences, Federal University of Santa Catarina, Florianopolis, Santa Catarina 88040-900, Brazil Medicine School, Division of Health Sciences, Anahuac Mayab University, Merida, Yucat an 97310, Mexico d Faculty of Human Sciences, Medical School Hamburg, University of Applied Science and Medical University, Hamburg 20457, Germany

journal of sport and health science/journal of sport and health science

Standardization of exercise intensity and consideration of a dose–response is essential. Commentary on “Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models”, by Lourenco et al., published 2019 in Nature Medicine