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ObjectivesWe report our two years clinical, and echo follow up of patients who underwent trans-apical and trans-femoral TAVI.MethodsAll patients who underwent TAVI therapy have been followed at six, 12, and 24 months, where clinical, and echo evaluation have been obtained.ResultsSixty-six pat were operated, with mean age of 78.7±9.3 y, 53% females, and 47% males. The mean logistic Euro score was 21±8. 55% of pat completed 2 years follow-up. Fourty-two pat received Edward Sapien valve (25 trsna-apical, and 17 trans-femoral ), and 24 pat received core valve. Thirty days mortality in Sapien valve group was 11%, and 0% in Core valve group. CVA developed in 8% of the core valve group, and 7% of the Sapien valve group. Complete heart block developed in 37.5 of Core group, and 4.8% of the sapien group. Peripheral arterial complications occurred in 12.5% of Core patients, and 5.8% of Sapien patients. On follow up, patient’s symptoms improved. The PG decreased from 88±22mmHg to 19±7mmHg, P<0.0001, and the mitral regurgitation (MR) severity grade decreased from 1.6±1.1 to 0.9±0.6, P<0.001. Paravalvular leak was mild in 15.2%, and moderate in 6.1% of patients.ConclusionTAVI is promising technique in treating patients with severe AS with acceptable mortality rate. There was significant improvement in patient’s symptoms, reduction in aortic gradient and reduction in MR severity

Two years follow up of patients who underwent trans-catheter aortic valve implantation at Prince Sultan Cardiac Center (TAVI)