Open AccessHigh expression of LMO2 in Hodgkin, Burkitt and germinal center diffuse large B cell lymphomas
Author(s) -
Tahany M. Shams
Publication year - 2011
Publication title -
journal of the egyptian national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.398
H-Index - 22
eISSN - 2589-0409
pISSN - 1110-0362
DOI - 10.1016/j.jnci.2011.10.006
Subject(s) - germinal center , lymphoma , diffuse large b cell lymphoma , medicine , pathology , mantle cell lymphoma , immunohistochemistry , immunophenotyping , cancer research , b cell , immunology , antibody , antigen
The LMO2 gene encodes a transcription factor that regulates key events in erythropoiesis, angiogenesis, and embryogenesis and is highly expressed at the most immature stages of lymphopoiesis. Its implication in Hodgkin lymphoma (HL), Burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL) is limited in the literature.
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