Open AccessLipid-lowering, hepatoprotective, and atheroprotective effects of the mixture Hong-Qu and gypenosides in hyperlipidemia with NAFLD rats
Author(s) -
Sanhu Gou,
Haifeng Huang,
Xinyue Chen,
Jie Liu,
Miao He,
Yinyun Ma,
Xiaoning Zhao,
Yun Zhang,
Jingman Ni
Publication year - 2016
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1016/j.jcma.2015.09.002
Subject(s) - hyperlipidemia , fatty acid synthase , medicine , steatosis , endocrinology , fatty liver , lipid metabolism , carnitine , peroxisome , pharmacology , receptor , disease , diabetes mellitus
Hyperlipidemia and its complications are among the most harmful of diseases with a worldwide impact, which creates an urgent imperative to find safe and effective drugs for treatment. HG is mainly composed of two kinds of traditional Chinese medicines (TCM), Hong-Qu and gypenosides. Previously, the ingredients of the mixture mainly composed by Hong-Qu and gypenosides (HG) were widely used for purposes of lipid-lowering, antiatherosclerosis effects, and maintaining cardiovascular health in China. The purpose of this study was to determine whether HG provides any benefit to patients with hyperlipidemia.
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