Open AccessAntiallergic effect of Gami-hyunggyeyeongyotang on ovalbumin-induced allergic rhinitis in mouse and human mast cells
Author(s) -
Yong-Seok Im,
Bina Lee,
EunYoung Kim,
Ju-Hee Min,
Dea-Uk Song,
Jeong-Min Lim,
Ji Whan Eom,
Hyun Joo Cho,
Youngjoo Sohn,
HyukSang Jung
Publication year - 2016
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1016/j.jcma.2015.08.012
Subject(s) - ovalbumin , medicine , mucous membrane of nose , immunoglobulin e , eosinophil , immunology , sensitization , protein kinase a , p38 mitogen activated protein kinases , kinase , antibody , biology , immune system , biochemistry , asthma
Gami-hyunggyeyeongyotang (GMHGYGT) is a polyherbal medicine derived from an oriental prescription traditionally used in the treatment of allergic diseases such as allergic rhinitis (AR). This study aimed to evaluate the effects of GMHGYGT on ovalbumin (OVA) sensitization/challenge-induced AR in BALB/C mice, through examination of allergic inflammatory response regulation, as well as examination of human mast cells (HMC-1).
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