Open AccessAssessment of retinal pigment epithelial cells in epiretinal membrane formation
Author(s) -
LeiChi Wang,
Kuo-Hsuan Hung,
ChihChien Hsu,
ShihJen Chen,
Wing–Yin Li,
TaiChi Lin
Publication year - 2015
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1016/j.jcma.2015.01.003
Subject(s) - medicine , epiretinal membrane , pigment , retinal , ophthalmology , retinal pigment epithelium , membrane , microbiology and biotechnology , vitrectomy , biochemistry , visual acuity , biology , organic chemistry , chemistry
The definite etiology of epiretinal membrane (ERM) is unknown. Clinically, ERM may cause metamorphopsia and decreased vision during the disease exacerbation. Several theories of pathogenesis emphasize a glial tissue origin. However, in some studies, surgically removed ERM specimens were found to contain retinal pigment epithelial (RPE) cells. The actual mechanism by which RPE cells gain access into the inner retina and what roles they play in the formation of ERM remain controversial. The purpose of this study was to evaluate the incidence of RPE cells in ERM and discuss the possible mechanisms.
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