Open AccessDiscovery and characterization of small-molecule inhibitors of NLRP3 and NLRC4 inflammasomes
Author(s) -
Maria Sebastian-Valverde,
Henry Wu,
Md Al Rahim,
Roberto Sánchez,
Kunal Kumar,
Robert J. De Vita,
Giulio Maria Pasinetti
Publication year - 2021
Publication title -
journal of biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.361
H-Index - 513
eISSN - 1067-8816
pISSN - 0021-9258
DOI - 10.1016/j.jbc.2021.100597
Subject(s) - inflammasome , pyrin domain , pharmacophore , nlrc4 , virtual screening , docking (animal) , aim2 , computational biology , small molecule , effector , chemistry , microbiology and biotechnology , biology , biochemistry , caspase 1 , receptor , medicine , nursing
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