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The interaction of multiple Coronal Mass Ejections (CMEs) has been observedby LASCO coronagraphs and by near-Earth spacecraft, and it is thought to be animportant cause of geo-effective storms, large Solar Energetic Particles eventsand intense Type II radio bursts. New and future missions such as STEREO, theLWS Sentinels, and the Solar Orbiter will provide additional observations ofthe interaction of multiple CMEs between the Sun and the Earth. We present theresults of simulations of two and more CMEs interacting in the innerheliosphere performed with the Space Weather Modeling Framework (SWMF). Basedon those simulations, we discuss the observational evidence of the interactionof multiple CMEs, both in situ and from coronagraphs. The clearest evidence ofthe interaction of the CMEs are the large temperature in the sheath, due to theshocks merging, and the brightness increase in coronagraphic images, associatedwith the interaction of the leading edges. The importance of having multiplesatellites at different distances and angular positions from the Sun is alsodiscussed.

Observational evidence of CMEs interacting in the inner heliosphere as inferred from MHD simulations