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The role of serum procalcitonin in the diagnosis of bacterial meningitis in adults: a systematic review and meta-analysis
Author(s) -
Jens Vikse,
Brandon Michael Henry,
Joyeeta Roy,
Piravin Kumar Ramakrishnan,
Krzysztof A. Tomaszewski,
Jerzy Walocha
Publication year - 2015
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2015.07.011
Subject(s) - procalcitonin , confidence interval , medicine , diagnostic odds ratio , odds ratio , meningitis , viral meningitis , likelihood ratios in diagnostic testing , meta analysis , gastroenterology , bacterial meningitis , pediatrics , sepsis
Clinically, it is often difficult to differentiate between bacterial and viral aetiologies in adults with suspected meningitis. Several studies have demonstrated the potential use of serum procalcitonin (PCT) in making this differentiation. The aim was to pool these studies into a meta-analysis to determine the diagnostic accuracy of PCT.

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