Open AccessProtective effects of Sm-p80 in the presence of resiquimod as an adjuvant against challenge infection with Schistosoma mansoni in mice
Author(s) -
Gul Ahmad,
Weidong Zhang,
Workineh Torben,
Zahid Noor,
Afzal A. Siddiqui
Publication year - 2010
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2010.02.2266
Subject(s) - adjuvant , schistosoma mansoni , recombinant dna , biology , immunology , antibody titer , antibody , virology , titer , schistosomiasis , helminths , biochemistry , gene
To determine the prophylactic efficacy of an Sm-p80-based vaccine formulation against challenge infection with Schistosoma mansoni in mice using an approach comprising of initial priming with DNA and boosting with recombinant protein in the presence of resiquimod (R848) as an adjuvant.
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