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In our previous in vitro study mid-myocardial relative to epicardial pacing decreased transmural dispersion of depolarization (TDR) and prevented ventricular arrhythmia. We therefore hypothesized that in vivo mid-myocardial pacing in canines has a similar effect.

In vivo effects of mid-myocardial pacing on transmural dispersion of repolarization and conduction in canines