English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

ber of patients evaluated from a single center, conclusions iarrhea is a major cause of morbidity during high-dose hemotherapy followed by autologous stem cell transplanation (ASCT). It occurs in almost half of recipients of ASCT nd generally, it is attributed to the effects of high-dose hemotherapy on the gastrointestinal mucosa and the effects f broad-spectrum antibiotic regimens for the prophylaxis and reatment of neutropenia. However, other etiologies might be onsidered, such as viral, bacterial and parasitic infections.1,2 Despite being the most common etiology of diarrhea after SCT, the conditioning regime is seldom implicated in severe omplications, with some exceptions. Cytarabine-containing egimens, high-dose melphalan (≥200 mg/m2), and regimens ontaining multiple alkylating agents may cause more severe iarrhea.3 Conversely, infectious causes of diarrhea are less prevalent han damage from conditioning therapy. Clostridium difficile is onsidered the leading cause of infectious diarrhea among ospitalized patients and is a major concern in immunosupressed individuals.4 Viruses such as cytomegalovirus (CMV) nd some serotypes of adenovirus might also be implicated in iarrhea after ASCT, but rarely cause life-threatening compliations. Diarrhea secondary to intestinal parasite infection, uch as Cryptosporidium, Giardia lamblia, Entamoeba histolyica and helminths, is rare among patients who come to

Diarrhea after autologous stem cell transplantation in low-middle income countries: is Clostridium difficile the most prevalent infectious etiology?