Germline rare variants of lectin pathway genes predispose to asymptomatic SARS-CoV-2 infection in elderly individuals | Zendy

Giuseppe D’Alterio | Zendy; Vito Alessandro Lasorsa | Zendy; Ferdinando Bonfiglio | Zendy; Sueva Cantalupo | Zendy; Barbara Eleni Rosato | Zendy; Immacolata Andolfo | Zendy; Roberta Russo | Zendy; Umberto Esposito | Zendy; Giulia Frisso | Zendy; Pasquale Abete | Zendy; Gian Marco Cassese | Zendy; Giuseppe Servillo | Zendy; Ivan Gentile | Zendy; Carmelo Piscopo | Zendy; Matteo Della Monica | Zendy; Giuseppe Fiorentino | Zendy; Angelo Boccia | Zendy; Giovanni Paolella | Zendy; Veronica Ferrucci | Zendy; Pasqualino De Antonellis | Zendy; Roberto Siciliano | Zendy; Fathem Asadzadeh | Zendy; Pellegrino Cerino | Zendy; Carlo Buonerba | Zendy; Biancamaria Pierri | Zendy; Massimo Zollo | Zendy; Achille Iolascon | Zendy; Mario Capasso | Zendy

AI Assistant Blog Pricing

Open Access

Germline rare variants of lectin pathway genes predispose to asymptomatic SARS-CoV-2 infection in elderly individuals

Author(s) -

Giuseppe D’Alterio,

Vito Alessandro Lasorsa,

Ferdinando Bonfiglio,

Sueva Cantalupo,

Barbara Eleni Rosato,

Immacolata Andolfo,

Roberta Russo,

Umberto Esposito,

Giulia Frisso,

Pasquale Abete,

Gian Marco Cassese,

Giuseppe Servillo,

Ivan Gentile,

Carmelo Piscopo,

Matteo Della Monica,

Giuseppe Fiorentino,

Angelo Boccia,

Giovanni Paolella,

Veronica Ferrucci,

Pasqualino De Antonellis,

Roberto Siciliano,

Fathem Asadzadeh,

Pellegrino Cerino,

Carlo Buonerba,

Biancamaria Pierri,

Massimo Zollo,

Achille Iolascon,

Mario Capasso

Publication year - 2022

Publication title -

genetics in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.509

H-Index - 128

eISSN - 1530-0366

pISSN - 1098-3600

DOI - 10.1016/j.gim.2022.04.007

Subject(s) - asymptomatic , exome sequencing , medicine , asymptomatic carrier , gene , phenotype , biology , immunology , genetics

Emerging evidence suggest that infection-dependent hyperactivation of complement system (CS) may worsen COVID-19 outcome. We investigated the role of predicted high impact rare variants - referred as qualifying variants (QVs) - of CS genes in predisposing asymptomatic COVID-19 in elderly individuals, known to be more susceptible to severe disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom

About

About Careers Publisher Partners Contact Us Our institutional solutions Get Organisational Trial or Quote

Learn

FAQs Blog Terms of Use Privacy Policy

Download the Zendy App

Discover

Explore

Home ZAIA Blog