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A s anyone who provides care in a dialysis clinic is aware, pruritis is a common and debilitating symptom for patients receiving maintenance dialysis. In a recent survey from the Dialysis Outcomes and Practice Patterns Study group encompassing 17 countries, nearly 1 in 5 patients (18%) were “extremely” or “very much” troubled by “itchy skin,” a total that rose to nearly 3 in 8 (37%) when moderate symptoms were included. As would be expected, chronic itching impairs quality of life. Unfortunately, physicians do not fully appreciate the burden of pruritis, with dialysis unit medical directors underestimating the prevalence in 69% of units. This may be because 1 in 6 patients reports not having alerting facility staff to the symptoms. For at least 3 reasons, nephrologists and other providers should take pruritis very seriously. First,

Pruritis: A Vexing Problem With a Promising New Therapy