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Absence of the falx cerebri is a rare radiological finding, which is generally described in relation with varying degrees of holoprosencephaly or other structural central nervous system anomalies. We present a case of non-syndromic, asymptomatic absence of falx cerebri in an elderly patient, which was discovered incidentally on a computed tomography examination of the head. The superior sagittal sinus was narrowed, but present. Relevant anatomic and embryological considerations are discussed, as well as potential implications for clinical practice.

Incidentally detected total agenesis of the falx cerebri: Potential significance of this rare finding