English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Purpose: To evaluate the diagnostic performance of 18F-flurodeoxyglucose positron emission tomography/contrast enhanced computed tomography (18F-FDG PET/CT) in patients with clinically/radiologically suspected ovarian tumor recurrence and normal tumor markers.Materials and methods: A total of 54 18F-FDG PET/CT studies from 41 patients with suspected ovarian tumor recurrence and normal tumor markers were evaluated. Each patient underwent PET/CT with CE-CT scans in the same study. Studies were read independently by one experienced nuclear medicine physician and one experienced radiologist. A four-point score (score 0 = definitely benign, score 1 = probably benign, score 2 = probably malignant and score 3 = definitely malignant) used to assess the presence or absence of recurrence (local, regional or distant). The final diagnosis of tumor status was made on the basis of subsequent follow-up by conventional imaging (CT/MRI), 18F-18F-FDG PET/CT or histopathology whenever possible.Results: Of the 54 studies evaluated, 26 (48%) studies had tumor recurrence and 28 (52%) studies were disease-free based on final diagnosis.Combined 18F-FDG PET/CT vs. CE-CT alone showed sensitivity, specificity and accuracy of 92% vs. 73%, 90% vs. 55%, and 91% vs. 63%, respectively. 18F-18F-FDG PET/CT was significantly more sensitive, more specific and more accurate compared to CE-CT with P-values of 0.06, 0.006 and 0.0001, respectively. Site-based analyses were also performed and showed significantly higher diagnostic indices for combined FDG-PET/CT.Conclusion: Combined 18F-FDG PET/CT with contrast enhancement is more accurate than CE-CT alone in the diagnosis of ovarian tumor recurrence in patients with normal tumor markers

Role of 18F-FDG PET/CT in the detection of ovarian cancer recurrence in the setting of normal tumor markers