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Mitral stenosis is a disease almost exclusively due to rheumatic cardit . Mitral stenosis is a "Diastolic event". Basically it is an obstruction of the filling of the left ventricle at a level of a mitral valve. This brings a diastolic atrio-ventricular pressure gradient. Severe mitral stenosis (MVA <1.0cm2) leads to pressure overload of the left atrium with dilatation of it and pulmonary venous hypertension Then comes a secondary pulmonary arterial hypertension, which in turns lead to pressure overload of the right ventricle with right ventricle dysfunction with dilatation and secondary tricuspid regurgitation.

Cardiac silhouette following a mitral valve replacement, tricuspid annuloplasty and atrioplasty of both atria