Open AccessNeuroimmune interactions in patients with inflammatory bowel diseases: Disease activity and clinical behavior based on Substance P serum levels
Author(s) -
Francesca Tavano,
Fabio F. di Mola,
Anna Latiano,
Orazio Palmieri,
Fabrizio Bossa,
Maria Rosa Valvano,
Tiziana Latiano,
Vito Annese,
Angelo Andriulli,
Pierluigi Di Sebastiano
Publication year - 2011
Publication title -
journal of crohn s and colitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.277
H-Index - 80
eISSN - 1876-4479
pISSN - 1873-9946
DOI - 10.1016/j.crohns.2011.11.004
Subject(s) - ulcerative colitis , medicine , inflammatory bowel disease , substance p , crohn's disease , gastroenterology , disease , pathophysiology , colitis , neuropeptide , inflammation , immunology , receptor
The neuropeptide Substance P, plays a key role in modulating neuroimmune interactions in patients with inflammatory bowel diseases. We analyzed Substance P serum levels in patients with ulcerative colitis and Crohn's disease, to detail the involvement of the neuropeptide in the pathophysiology of these disorders.
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